Endocrine Abstracts

Introduction: Plasma metanephrines (PMETS) are widely used as a first-line investigation for phaeochromocytoma/paraganglioma owing to the high diagnostic sensitivity of the test. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the methodology of choice for measuring PMETS due to the high analytical specificity of the technique. However, there have been recent reports of interference in LC-MS/MS PMETS assays by the α1-recept...

Introduction: Plasma metanephrines (PMETS) are widely used as a first-line investigation for phaeochromocytoma/paraganglioma owing to the high diagnostic sensitivity of the test. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) has become the methodology of choice for measuring PMETS due to the high analytical specificity of the technique. However, there have been recent reports of interference in LC-MS/MS PMETS assays by the α1-recept...